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2.1 --- a/grant.html Tue Apr 21 05:58:31 2009 -0700 2.2 +++ b/grant.html Tue Apr 21 06:11:15 2009 -0700 2.3 @@ -661,10 +661,10 @@ 2.4 ∙July 2010 (milestone): Submit a paper describing combinations of marker genes for each cortical area, and a small 2.5 number of marker genes that can, in combination, define most of the areas at once 2.6 Revealing new ways to parcellate a structure into regions 2.7 -∙April-March 2011: Explore dimensionality reduction algorithms for Aim 2. Explore standard hierarchial clustering 2.8 -algorithms, used in combination with dimensionality reduction, for Aim 2. Explore co-clustering algorithms. Think 2.9 -about how radial profile information can be used for Aim 2. Adapt clustering algorithms to use radial profile in- 2.10 -formation. Quantitatively compare the performance of different dimensionality reduction and clustering techniques. 2.11 +∙June 2010-March 2011: Explore dimensionality reduction algorithms for Aim 2. Explore standard hierarchial clus- 2.12 +tering algorithms, used in combination with dimensionality reduction, for Aim 2. Explore co-clustering algorithms. 2.13 +Think about how radial profile information can be used for Aim 2. Adapt clustering algorithms to use radial profile 2.14 +information. Quantitatively compare the performance of different dimensionality reduction and clustering techniques. 2.15 Quantitatively compare the value of different flatmapping methods and ways of representing radial profiles. 2.16 ∙March 2011 (milestone): Submit a paper describing a method fulfilling Aim 2. Release toolbox. 2.17 ∙February-May 2011: Using the methods developed for Aim 2, explore the genomic anatomy of the cortex. If new ways

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5.1 --- a/grant.txt Tue Apr 21 05:58:31 2009 -0700 5.2 +++ b/grant.txt Tue Apr 21 06:11:15 2009 -0700 5.3 @@ -542,7 +542,7 @@ 5.4 * July 2010 (milestone): Submit a paper describing combinations of marker genes for each cortical area, and a small number of marker genes that can, in combination, define most of the areas at once 5.5 5.6 === Revealing new ways to parcellate a structure into regions === 5.7 -* April-March 2011: Explore dimensionality reduction algorithms for Aim 2. Explore standard hierarchial clustering algorithms, used in combination with dimensionality reduction, for Aim 2. Explore co-clustering algorithms. Think about how radial profile information can be used for Aim 2. Adapt clustering algorithms to use radial profile information. Quantitatively compare the performance of different dimensionality reduction and clustering techniques. Quantitatively compare the value of different flatmapping methods and ways of representing radial profiles. 5.8 +* June 2010-March 2011: Explore dimensionality reduction algorithms for Aim 2. Explore standard hierarchial clustering algorithms, used in combination with dimensionality reduction, for Aim 2. Explore co-clustering algorithms. Think about how radial profile information can be used for Aim 2. Adapt clustering algorithms to use radial profile information. Quantitatively compare the performance of different dimensionality reduction and clustering techniques. Quantitatively compare the value of different flatmapping methods and ways of representing radial profiles. 5.9 * March 2011 (milestone): Submit a paper describing a method fulfilling Aim 2. Release toolbox. 5.10 * February-May 2011: Using the methods developed for Aim 2, explore the genomic anatomy of the cortex. If new ways of organizing the cortex into areas are discovered, read the literature and talk to people to learn about research related to interpreting our results. Create documentation and unit tests for software toolbox for Aim 2. Respond to user bug reports for Aim 2 software toolbox. 5.11 * May 2011 (milestone): Submit a paper on the genomic anatomy of the cortex, using the methods developed in Aim 2