# HG changeset patch # User bshanks@bshanks.dyndns.org # Date 1239618702 25200 # Node ID 01c118d1074ba2bb3c2a6bcf05cace1ae0e4b9da # Parent 5db0420abbb6426c36371d724b77a50d5c5f5048 . --- a/grant.html Mon Apr 13 03:25:42 2009 -0700 +++ b/grant.html Mon Apr 13 03:31:42 2009 -0700 @@ -52,7 +52,7 @@ gene expression dataset used in the construction of the classifier is called training data. In the machine learning literature, this sort of procedure may be thought - of as a supervised learning task, defined as a task in whcih the goal is to learn + of as a supervised learning task, defined as a task in which the goal is to learn a mapping from instances to labels, and the training data consists of a set of instances (voxels) for which the labels (subregions) are known. Each gene expression level is called a feature, and the selection of which @@ -489,6 +489,7 @@ app2 has examples of genetic targeting to specific anatomical regions — note: + do we need to cite: no known markers? impressive results? 14 Binary file grant.odt has changed Binary file grant.pdf has changed --- a/grant.txt Mon Apr 13 03:25:42 2009 -0700 +++ b/grant.txt Mon Apr 13 03:31:42 2009 -0700 @@ -29,7 +29,7 @@ The object of aim 1 is not to produce a single classifier, but rather to develop an automated method for determining a classifier for any known anatomical structure. Therefore, we seek a procedure by which a gene expression dataset may be analyzed in concert with an anatomical atlas in order to produce a classifier. Such a procedure is a type of a machine learning procedure. The construction of the classifier is called __training__ (also __learning__), and the initial gene expression dataset used in the construction of the classifier is called __training data__. -In the machine learning literature, this sort of procedure may be thought of as a __supervised learning task__, defined as a task in whcih the goal is to learn a mapping from instances to labels, and the training data consists of a set of instances (voxels) for which the labels (subregions) are known. +In the machine learning literature, this sort of procedure may be thought of as a __supervised learning task__, defined as a task in which the goal is to learn a mapping from instances to labels, and the training data consists of a set of instances (voxels) for which the labels (subregions) are known. Each gene expression level is called a __feature__, and the selection of which genes to include is called __feature selection__. Feature selection is one component of the task of learning a classifier. Some methods for learning classifiers start out with a separate feature selection phase, whereas other methods combine feature selection with other aspects of training. @@ -316,3 +316,5 @@ --- note: + +do we need to cite: no known markers? impressive results?