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5 == Budget Justification ==

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7 Because the anticipated product is mainly intellectual property (approaches for extracting information from

8 large data sets of a particular sort), this work depends most heavily on personnel, as reflected in the budget.

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10 \vspace{0.3cm} \noindent **A. Senior/Key Person**

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12 \noindent 1. Charles F. Stevens, M.D., Ph.D., Principal Investigator (effort \= 4.80 calendar months), will direct the

13 project, engage in improving the computational approaches from the ones currently being used, contribute

14 to developing the mathematical basis for the algorithms, participate in the interpretation of data, and write

15 drafts of journal articles. Stevens is known for combining theory with experiment, is trained in physics and

16 mathematics as well as in biology, and has been using computation approaches to data analysis for many

17 years in many different contexts.

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19 In the subsequent year a 3% increment has been calculated.

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21 \vspace{0.3cm} \noindent **B. Other Personnel**

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23 \indent Postdoctoral Associates.

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25 To be named, Ph.D., Research Associate (effort \= 12 calendar months), trained in computational

26 techniques and machine learning to work collaboratively on the problem of deriving cortical arealization from

27 gene expression patterns.

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29 Graduate Students.

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31 Baylis Shanks, M.S. (effort \= 12 calendar months), is currently working on the project for his thesis.

32 Shanks is currently in the Computational Neuroscience program at the University of California, San Diego,

33 and has been primarily responsible for applying the suite of standard approaches to the problem of

34 identifying genetic tags that identify cortical areas. He is well trained in computational methods for the

35 analysis of large data sets, and is at home with neurobiology.

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37 \vspace{0.3cm} \noindent **D. Travel**

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39 \noindent 1. Domestic. Funds are requested to cover the cost of attending three scientific meetings to present work

40 related to this project at \$1,500 each (airfare, ground transportation, registration, lodging, meals).

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42 \vspace{0.3cm} \noindent **F. Other Direct Costs**

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44 \noindent 1. Material and Supplies. Computer related consumables, software licenses \$11,000; computer

45 equipment, including mass storage \$6,000.

46 \\2. Publication costs. Graphics, page charges, and reprints.

47 \\4. ADP/Computer Services. Institutional computer services and network access charges.

48 \\8. Central Services. Institutional services for which investigators are charged on a fee-for-use basis

49 include lab support shop, small equipment repair and maintenance, photocopying, and postage.

50 \\9. Graduate Student Fees. The University of California, San Diego resident fees for 2009-2010 are

51 currently estimated at \$10,945, and a portion (\$5,468) is budgeted so that in year 1 the combined

52 salary/benefits/fees amount does not exceed the maximum amount allowed by NIH (\$37,368).

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