1.1 --- a/grant.txt Mon Apr 13 03:43:51 2009 -0700 1.2 +++ b/grant.txt Mon Apr 13 03:52:58 2009 -0700 1.3 @@ -1,3 +1,6 @@ 1.4 +\documentclass{nih} 1.5 +\piname{Stevens, Charles F.} 1.6 + 1.7 == Specific aims == 1.8 1.9 Massive new datasets obtained with techniques such as in situ hybridization (ISH) and BAC-transgenics allow the expression levels of many genes at many locations to be compared. Our goal is to develop automated methods to relate spatial variation in gene expression to anatomy. We want to find marker genes for specific anatomical regions, and also to draw new anatomical maps based on gene expression patterns. We have three specific aims:\\ 1.10 @@ -167,10 +170,10 @@ 1.11 Gnee mtif2\footnote{"mitochondrial translational initiation factor 2"; EntrezGene ID 76784} is shown in figure the upper-right of Fig. \ref{MOcombo}. Mtif2 captures MO's upper-left boundary, but not its lower-right boundary. Mtif2 does not express very much on the medial surface. By adding together the values at each pixel in these two figures, we get the lower-left of Figure \ref{MOcombo}. This combination captures area MO much better than any single gene. 1.12 1.13 \begin{figure}\label{MOcombo} 1.14 -\includegraphics[scale=.4]{MO_vs_Wwc1_jet.eps} 1.15 -\includegraphics[scale=.4]{MO_vs_Mtif2_jet.eps} 1.16 - 1.17 -\includegraphics[scale=.4]{MO_vs_Wwc1_plus_Mtif2_jet.eps} 1.18 +\includegraphics[scale=.36]{MO_vs_Wwc1_jet.eps} 1.19 +\includegraphics[scale=.36]{MO_vs_Mtif2_jet.eps} 1.20 + 1.21 +\includegraphics[scale=.36]{MO_vs_Wwc1_plus_Mtif2_jet.eps} 1.22 \caption{Upper left: $wwc1$. Upper right: $mtif2$. Lower left: wwc1 + mtif2 (each pixel's value on the lower left is the sum of the corresponding pixels in the upper row). Within each picture, the vertical axis roughly corresponds to anterior at the top and posterior at the bottom, and the horizontal axis roughly corresponds to medial at the left and lateral at the right. The red outline is the boundary of region MO. Pixels are colored approximately according to the density of expressing cells underneath each pixel, with red meaning a lot of expression and blue meaning little.} 1.23 \end{figure} 1.24